frontal lobe

Performance in specific language tasks correlates with regional volume changes in progressive aphasia

BACKGROUND: Patterns of language impairment have long been used clinically to localize brain damage in stroke patients. The same approach might be useful in the differential diagnosis of progressive aphasia owing to neurodegenerative disease. …

Anatomical correlates of sentence comprehension and verbal working memory in neurodegenerative disease

This study investigates whether sentence comprehension and nonsyntactic verbal working memory (vWM) are sustained by the same or by different neural systems. Scores in a sentence-picture matching task and in digits backward (DB) were correlated with …

Anatomical correlates of early mutism in progressive nonfluent aphasia

Patients with progressive nonfluent aphasia (PNFA) can become mute early in the course of the disease. Voxel-based morphometry showed that PNFA is associated with left anterior insula and inferior frontal atrophy. In PNFA with early mutism, volume …