Clinical symptoms observed in Alzheimer's disease (AD) patients may reflect variations within specific large-scale brain networks, modeling AD as a disconnection syndrome. The present magnetic resonance imaging study aims to compare the organization …
Semantic deficits in Alzheimer's disease (AD) are often more severe for items that are characterized by a unique semantic and lexical association, such as famous people. Whether these deficits are due to the degradation of semantic information or a …
OBJECTIVE: Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects the corpus callosum (CC), which plays a key role in interhemispheric coupling in high-demand conditions. Using 3D callosal measurements and a letter-matching …
Modern cognitive neuroscientific theories and empirical evidence suggest that brain structures involved in movement may be related to action-related semantic knowledge. To test this hypothesis, we examined the naming of environmental sounds in …
Semantic deficits in Alzheimer's disease have been widely documented, but little is known about the integrity of semantic memory in the prodromal stage of the illness. The aims of the present study were to: (i) investigate naming abilities and …
OBJECTIVE: To investigate the neural correlates of verbal and nonverbal semantic processing in neurodegenerative disease. BACKGROUND: Semantic memory is often impaired in neurodegenerative disease. Neuropsychologic and functional neuroimaging studies …
Good cognitive performance requires adherence to rules specific to the task at hand. Patients with neurological disease often make rule violation (RV) errors, but the anatomical basis for RV during cognitive testing remains debated. The present study …
Neuropsychological studies suggest that knowledge about living and nonliving objects is processed in separate brain regions. However, lesion and functional neuroimaging studies have implicated different areas. To address this issue, we used …