Language deficits in Alzheimer’s disease and semantic dementia

Patients with Alzheimer’s disease not only exhibit memory problems but may also manifest difficulty in finding the right word for objects or pictures at early stages of the disease. However, these symptoms often represent the early manifestation of another dementia syndrome, a semantic variant of Primary Progressive Aphasia (PPA-SV).

The general goal of this research proposal is to better understand and differentiate between the nature of these language deficits and the anatomical features of these patients. To achieve this goal, a set of experimental language measures and sophisticated imaging approaches will be combined. This represents a fundamental challenge in the field of Alzheimer’s disease and related dementia research.

In fact, understanding the nature of the language deficits in diseases of dementia may be beneficial for :

  1. developing specific language rehabilitation programs
  2. recommending communication strategies for caregivers and family members to improve social interactions